Cytokine Signalling Forum

Publications





March 19

Augmentation de LDL-C et HDL-C induit par le Baricitinib dans le cas de la polyarthrite rhumatoïde: une méta-analyse d’essais contrôlés randomisés

Qiu C, Zhao X, She L, Shi Z, Deng Z, Tan L, Tu X, Jiang S, Tang B.
Lipids Health Dis. 2019 Feb 18;18(1):54.

This study confirmed that BARI induced a stable dose-dependent increase in LDL-C and HDL-C levels. There was no significant difference of CV risk between BARI and placebo groups. High risk of CV events is strongly associated with RA. Mechanisms underlying the excess risk of CV events in RA remains unclear. This study aims to provide additional insight into the clinical safety of BARI, focusing on the effects of BARI on LDL-C and HDL-C levels and CV risk. A Cochrane analysis was performed on s...

Mots clefs: JAK, Baricitinib, Clinical, Safety

Traduit par: Farese