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An Update on Patient Reported Outcomes with JAKinibs

Developed by CESAS Medical, under the auspices of the University of Glasgow This activity is supported by unrestricted educational grants from Pfizer and Lilly

Release date: 19 June 2020
Estimated time to complete activity: 1 and 1/2 hours
Compatible with all modern internet browsers and mobile devices

EDUCATIONAL OBJECTIVES
After completing this activity, the learner will be able to:
  • Understand the impact of pain and fatigue as a patient-reported outcome
  • Explain the importance of depression and sleep in the management of RA
  • Understand patient-reported outcomes from Phase 3 JAKinib data
  • Discuss patient preference and satisfaction of RA treatment

TARGET AUDIENCE
This activity is designed for qualified rheumatologists of all levels of seniority, and other healthcare professionals involved in treating patients with inflammatory disease.

PROGRAMME OVERVIEW
ACR 2019 presented new scientific and clinical information on cytokine signalling science that will shape the rheumatology treatment landscape. Presented data include the impact of pain and fatigue as a patient-reported outcomes (PROs), importance of mental health and quality of life, patient-reported outcomes from Phase 3 JAKinib data and patient perspectives in the management of RA.

In this activity, An Update on Patient Reported Outcomes with JAKinibs, international experts review key abstracts and data specifically relating to PROs and patient perspectives. The 4 modules in this course specifically focuses on pain and fatigue as PROs, quality of life such as depression and sleep, PROs from approved RA treatments (upadacitinib, baricitinib and tofacitinib), and finally patient preferences and treatment satisfaction.

This course, An Update on Patient Reported Outcomes with JAKinibs, outlines recent developments in the cytokine signalling science and management of PROs in rheumatoid arthritis, and highlights and discusses the importance of these new data for clinical practice. The learner’s understanding of the information presented will be assessed following each of the course modules.

INSTRUCTIONS FOR PARTICIPATION
Participants must 1) read the activity information; 2) study the educational activity; 3) successfully complete the post-module assessments with a score of 80% or better; 4) and complete the evaluation form.

DISCLOSURE OF CONFLICTS OF INTEREST
CESAS Medical requires faculty, presenters, planners, managers, writers, and any other individuals who are in a position to influence the content of this activity to disclose any real and/or apparent conflict of interest (COI) they may have as related to the content of this activity. All identified COI are thoroughly reviewed and resolved according to CESAS Medical policy.
Module Presenter Video Questions
Introduction
Professor Johannes W.J. Bijlsma image
Professor Johannes W.J. Bijlsma

Professor and Head of the Department of Rheumatology and Clinical Immunology,
University Medical Centre, Utrecht, The Netherlands

Professor Bijlsma is the past President of EULAR (2017-2019), and a Professor of Rheumatology at the University Medical Centre, Utrecht, The Netherlands.

He acquired his Medical degree and PhD from the University of Utrecht and has been a Professor of Rheumatology since 1990. Professor Bijlsma was the Chairman of The EULAR Standing Committee on Education and Training, EULAR Educational Officer and has been EULAR Treasurer. He has also held a variety of roles from 1992-2008 at the Dutch Society for Rheumatology, including Scientific Secretary, President and Chairman Consilium. He is chairman of the Advisory Board of the Annals of Rheumatic Diseases and is on the editorial board of Clinical and Experimental Rheumatology, Best Practice & Research Clinical Rheumatology and Clinical Rheumatology.

Professor Bijlsma researches and specialises in immune aspects of rheumatic diseases and Osteoarthritis. He has authored and co-authored over 800 articles published in peer-reviewed international journals, has contributed chapters in a number of textbooks, and has edited and co-edited several books in the field of Rheumatology, including the EULAR Textbooks.

Prof. Johannes W.J. Bijlsma (Bio)
02:22
Pain and Fatigue as a Patient-Reported Outcome
Professor Johannes W.J. Bijlsma image
Professor Johannes W.J. Bijlsma

Professor and Head of the Department of Rheumatology and Clinical Immunology,
University Medical Centre, Utrecht, The Netherlands

Professor Bijlsma is the past President of EULAR (2017-2019), and a Professor of Rheumatology at the University Medical Centre, Utrecht, The Netherlands.

He acquired his Medical degree and PhD from the University of Utrecht and has been a Professor of Rheumatology since 1990. Professor Bijlsma was the Chairman of The EULAR Standing Committee on Education and Training, EULAR Educational Officer and has been EULAR Treasurer. He has also held a variety of roles from 1992-2008 at the Dutch Society for Rheumatology, including Scientific Secretary, President and Chairman Consilium. He is chairman of the Advisory Board of the Annals of Rheumatic Diseases and is on the editorial board of Clinical and Experimental Rheumatology, Best Practice & Research Clinical Rheumatology and Clinical Rheumatology.

Professor Bijlsma researches and specialises in immune aspects of rheumatic diseases and Osteoarthritis. He has authored and co-authored over 800 articles published in peer-reviewed international journals, has contributed chapters in a number of textbooks, and has edited and co-edited several books in the field of Rheumatology, including the EULAR Textbooks.

Prof. Johannes W.J. Bijlsma (Bio)
32:05 8
Quality of Life: Depression and Sleep
Professor Rieke Alten image
Professor Rieke Alten

Head of Department of Internal Medicine, Rheumatology,
Schlosspark-Klinik, University Medicine Berlin, Germany

Dr Rieke Alten is head of the department of internal Medicine, Rheumatology, Clinical Immunology, Osteology at Schlosspark-Klinik at University Medicine Berlin, where she also serves as the director of the Rheumatology Research Centre. She is a member of the Global Alliance for Patient Access and OMERACT Steering Committee of the Flare in Rheumatoid Arthritis Group. Dr Alten has served as a board member on many occasions for; German Medical Association, the institute for approval of drugs for the German Ministry of Health, “Kaiser-Friedrich-Stiftung” for postgraduate education in Germany and board member of the German Society of Rheumatology.
Prof. Rieke Alten (Bio)
24:29 5
Patient Reported Outcomes from RA Treatments
Professor Janet Pope image
Professor Janet Pope

Professor of Medicine in the Division of Rheumatology,
University of Western Ontario Schulich School of Medicine

Professor Pope is a Professor of Medicine in the Division of Rheumatology at the University of Western Ontario, Schulich School of Medicine, and Division Head in Rheumatology at St Joseph's Health Care in London, Ontario, Canada.

She obtained her Masters degree in Public Health and Fellowship in Rheumatology from Boston University. She then completed a Canadian Arthritis Society Research Fellow in Scleroderma. She is a section editor of Arthritis & Rheumatology, and on the Editorial Boards of Journal of Rheumatology, Nature Reviews Rheumatology, Lancet Rheumatology, RMD Open.

Her research includes epidemiologic studies in scleroderma, systemic lupus erythematosus (SLE) and RA, including outcome measurements, clinical trials and disease manifestations. She has published over 500 peer-reviewed articles, 15 chapters, 600 abstracts, and several Cochrane meta-analysis reviews.

Prof. Janet Pope (Bio)
25:04 7
Patient Perspectives in the Management of RA
Professor Johannes W.J. Bijlsma image
Professor Johannes W.J. Bijlsma

Professor and Head of the Department of Rheumatology and Clinical Immunology,
University Medical Centre, Utrecht, The Netherlands

Professor Bijlsma is the past President of EULAR (2017-2019), and a Professor of Rheumatology at the University Medical Centre, Utrecht, The Netherlands.

He acquired his Medical degree and PhD from the University of Utrecht and has been a Professor of Rheumatology since 1990. Professor Bijlsma was the Chairman of The EULAR Standing Committee on Education and Training, EULAR Educational Officer and has been EULAR Treasurer. He has also held a variety of roles from 1992-2008 at the Dutch Society for Rheumatology, including Scientific Secretary, President and Chairman Consilium. He is chairman of the Advisory Board of the Annals of Rheumatic Diseases and is on the editorial board of Clinical and Experimental Rheumatology, Best Practice & Research Clinical Rheumatology and Clinical Rheumatology.

Professor Bijlsma researches and specialises in immune aspects of rheumatic diseases and Osteoarthritis. He has authored and co-authored over 800 articles published in peer-reviewed international journals, has contributed chapters in a number of textbooks, and has edited and co-edited several books in the field of Rheumatology, including the EULAR Textbooks.

Prof. Johannes W.J. Bijlsma (Bio)
Professor Rieke Alten image
Professor Rieke Alten

Head of Department of Internal Medicine, Rheumatology,
Schlosspark-Klinik, University Medicine Berlin, Germany

Dr Rieke Alten is head of the department of internal Medicine, Rheumatology, Clinical Immunology, Osteology at Schlosspark-Klinik at University Medicine Berlin, where she also serves as the director of the Rheumatology Research Centre. She is a member of the Global Alliance for Patient Access and OMERACT Steering Committee of the Flare in Rheumatoid Arthritis Group. Dr Alten has served as a board member on many occasions for; German Medical Association, the institute for approval of drugs for the German Ministry of Health, “Kaiser-Friedrich-Stiftung” for postgraduate education in Germany and board member of the German Society of Rheumatology.
Prof. Rieke Alten (Bio)
Professor Janet Pope image
Professor Janet Pope

Professor of Medicine in the Division of Rheumatology,
University of Western Ontario Schulich School of Medicine

Professor Pope is a Professor of Medicine in the Division of Rheumatology at the University of Western Ontario, Schulich School of Medicine, and Division Head in Rheumatology at St Joseph's Health Care in London, Ontario, Canada.

She obtained her Masters degree in Public Health and Fellowship in Rheumatology from Boston University. She then completed a Canadian Arthritis Society Research Fellow in Scleroderma. She is a section editor of Arthritis & Rheumatology, and on the Editorial Boards of Journal of Rheumatology, Nature Reviews Rheumatology, Lancet Rheumatology, RMD Open.

Her research includes epidemiologic studies in scleroderma, systemic lupus erythematosus (SLE) and RA, including outcome measurements, clinical trials and disease manifestations. She has published over 500 peer-reviewed articles, 15 chapters, 600 abstracts, and several Cochrane meta-analysis reviews.

Prof. Janet Pope (Bio)
16:32 3
Close
Professor Johannes W.J. Bijlsma image
Professor Johannes W.J. Bijlsma

Professor and Head of the Department of Rheumatology and Clinical Immunology,
University Medical Centre, Utrecht, The Netherlands

Professor Bijlsma is the past President of EULAR (2017-2019), and a Professor of Rheumatology at the University Medical Centre, Utrecht, The Netherlands.

He acquired his Medical degree and PhD from the University of Utrecht and has been a Professor of Rheumatology since 1990. Professor Bijlsma was the Chairman of The EULAR Standing Committee on Education and Training, EULAR Educational Officer and has been EULAR Treasurer. He has also held a variety of roles from 1992-2008 at the Dutch Society for Rheumatology, including Scientific Secretary, President and Chairman Consilium. He is chairman of the Advisory Board of the Annals of Rheumatic Diseases and is on the editorial board of Clinical and Experimental Rheumatology, Best Practice & Research Clinical Rheumatology and Clinical Rheumatology.

Professor Bijlsma researches and specialises in immune aspects of rheumatic diseases and Osteoarthritis. He has authored and co-authored over 800 articles published in peer-reviewed international journals, has contributed chapters in a number of textbooks, and has edited and co-edited several books in the field of Rheumatology, including the EULAR Textbooks.

Prof. Johannes W.J. Bijlsma (Bio)
01:31
Evaluation 17

Date of preparation: 19 June 2020