Cytokine Signalling Forum


March 19

Baricitinib induz aumentos de LDL-C e HDL-C em Artrite Reumatoide: Uma Meta-análise de Ensaios Clínicos Randomizados

Qiu C, Zhao X, She L, Shi Z, Deng Z, Tan L, Tu X, Jiang S, Tang B.
Lipids Health Dis. 2019 Feb 18;18(1):54.

This study confirmed that BARI induced a stable dose-dependent increase in LDL-C and HDL-C levels. There was no significant difference of CV risk between BARI and placebo groups. High risk of CV events is strongly associated with RA. Mechanisms underlying the excess risk of CV events in RA remains unclear. This study aims to provide additional insight into the clinical safety of BARI, focusing on the effects of BARI on LDL-C and HDL-C levels and CV risk. A Cochrane analysis was performed on s...

Keywords: JAK, Baricitinib, Clinical, Safety

Translated by: Igor