Safety and Efficacy of Bimekizumab in Patients with Active Psoriatic Arthritis: 3-Year Results from a Phase 2b Randomized Controlled Trial and its Open-Label Extension Study

Arthritis Rheumatol 2022 doi: 10.1002/art.42280

In this investigation bimekizumab was associated with a sustained ACR50 improvement. This was highlighted following the attempt to describe the long-term safety, tolerability, and efficacy of up to three years of bimekizumab treatment in PsA patients

Adult patients with active PsA completing the double and dose-blind periods of the BE ACTIVE randomized controlled trial could enrol in the open-label extension (OLE) at
Week 48, after which patients received bimekizumab 160 mg every four weeks. Safety and efficacy results are presented through 152 Weeks, presenting a safety profile which was consistent with previous reports, with no new safety signals identified.


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