Secukinumab Improves Physical Function and Quality of Life and Inhibits Structural Damage in Patients with PsA with Sustained Remission or Low Disease Activity: Results From the 2-year Phase 3 FUTURE 5 Study
RMD Open 2023;9:e002939 doi 10.1136/rmdopen-2022-002939
Results from the 2-year phase 3 study FUTURE 5 show that the majority of patients with PsA who are treated with secukinumab were able to achieve sustained low disease activity or remission by week 104.
There is currently a limited understanding of the proportion of patients with PsA who achieve long term low disease activity or remission through treatment with secukinumab. Data from this study may reinforce the use of the Minimal Disease Activity index and the Disease Activity Index for Psoriatic Arthritis as treatment goals in PsA, as their achievement in this study has led to benefits in health-related quality of life and physical function.