Tasas de incidencia de enfermedad intersticial pulmonar en pacientes con artritis reumatoide tratados con tofacitinib
J Clin Rheumatol. 2021;27(8):e482–e490This post hoc analysis of pooled data from 21 clinical trials in the tofacitinib clinical trial programme highlights the importance of identifying known risk factors of RA-interstitial lung disease (ILD) in clinical practice.Citera, et al. investigated incidence rates of ILD – an extra-articular manifestation of RA – in patients with RA, receiving tofacitinib 5 or 10 mg BID and sort to identify potential risk factors for ILD in these patients....
Tasas de Incidencia de Eventos de Enfermedad Intersticial Pulmonar en Pacientes con Artritis Reumatoide Tratados con Tofacitinib
Journal of Clinical Rheumatology, Aug 2020 doi: 10.1097/RHU.0000000000001552.This study highlights the importance of accounting for known risk factors of RA-ILD in clinical practice. Interstitial lung disease (ILD) is an extra-articular manifestation of RA. The post-hoc investigated incidence rates of ILD in patients with RA, receiving tofacitinib 5 or 10 mg twice daily, and identified potential risk factors for ILD. This post-hoc analysis comprised a pooled analysis of patients receiving tofacitinib 5 or 10 mg twice daily or placebo from 21 Phase 1-4, and 2 long-term ex...