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May 2022

Impacto de tofacitinib em fadiga, sono e qualidade de vida relacionada à saúde em pacientes com artrite reumatoide: uma análise post hoc de dados de ensaios de fase 3

Arthritis Res Ther. 2022;24(1):83 doi:10.1186/s13075-022-02724-x

This was an exploratory post hoc analysis of pooled data, from over 2000 patients in three Phase 3 studies of tofacitinib, which demonstrates an association between tofacitinib treatment and significantly greater improvements in fatigue, sleep, and health-related quality of life (HRQoL), compared with placebo.