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Showing 1 result for “Miyasaka N”.

August 2018

Sospensione del Tocilizumab dopo Aver Raggiunto la Remissione in Pazienti con Artrite Reumatoide Trattati con Solo Tocilizumab o in Combinazione con Methotrexate: Risultati da uno Studio Prospettico Randomizzato Controllato (secondo anno dello studio SURPRISE)

Ann Rheum Dis 2018; 77:1268–1275 DOI: 10.1093/rheumatology/key121

The second-year results from the SURPRISE study show that low disease activity (LDA) can be maintained after discontinuation of tocilizumab with continued methotrexate after remission is achieved. Discontinuation of biologic agents in patients who have achieved remission or low disease activity (LDA) is desirable from a risk–benefit point of view. Compared with TNF inhibitors, little is known regarding TCZ-free remission or LDA, but studies indicate that only a small proportion of patients remai...

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