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Showing 2 results for “Naredo E”.

May 2022

Réponse au sécukinumab sur la synovite en utilisant l'échographie Doppler puissance dans le rhumatisme psoriasique : résultats à 12 semaines d'une étude de phase III, ULTIMATE

doi: 10.1093/rheumatology/keab628

D'Agostino, et al. aimed to evaluate whether treatment with secukinumab inhibits synovitis in patients with active PsA, as measured by PDUS. They found that secukinumab rapidly and significantly decreased synovitis, indicating a direct effect of IL-17 inhibition on the synovium in patients with PsA.


September 2018

Progression des Dommages Structuraux Chez les Patients Atteints de Polyarthrite Rhumatoïde Précoce Traités par Méthotrexate, Baricitinib ou Barictinib Plus Méthotrexate Selon la Réponse Clinique Dans l'Étude RA-BEGIN de Phase 3

Clinical Rheumatology 2018;37:2381–90 DOI 10.1007/s10067-018-4221-0

Patients with active RA and little or no prior DMARD treatment, who achieved sustained clinical responses, were less likely to show structural damage progression, irrespective of treatment.RA-BEGIN was a 52-week double-blind, multicentre Phase 3 trial, which assessed the safety and efficacy of BARI as monotherapy or in combination with MTX versus MTX monotherapy, in RA patients with no or limited prior DMARDs use.1-4 This post-hoc analysis evaluated the structural damage progression in patients ...