Relação entre o genótipo e a atividade da paraoxonase-1 e os principais eventos adversos cardiovasculares e neoplasias malignas em pacientes com artrite reumatoide que recebem tofacitinibe
J Rheumatol. 2023 doi 10.3899/jrheum.2023-0112 Epub ahead of print
High paraoxonase activity is associated with a significantly reduced risk of MACE and non-NMSC malignancies in white/European RA patients. The PON1 Q192R RR genotype had a significantly greater association with paraoxonase versus the QQ genotype, but had no significant association with MACE or non-NMSC malignancies.